I have about 5.5 TB on my main folder, and 1.5 TB on a secondary drive. Some of that 5.5 TB is symlinked to the secondary drive because I was running low on storage.
It's sorted into folders for gallery-dl, videos, pictures, forum threads downloaded with DownThemAll, stories, audio, SWFs, etc.
I have gallery-dl set as a scheduled task to run daily, to make sure I don't miss anything. Before gallery-dl, I was manually running RipMe on galleries. Now I don't have to worry about missing a day and having an artist disappear before the next time I check.
I've had to prune my collection because I don't have enough storage space for it all. Now, I focus more on the best content instead of trying to archive everything I encounter.