>>130080
Always have guard up on shut in, and her damage is typically pretty bad (most things resist it I've noticed)
If you're talking about the first two bosses (go drowned first), you can sell starting gear (knife+taser) to get $64. Buy large band-aids and maybe a bomb/gimmicky damage item from inflation lady. (Don't buy the inflation poppers, it makes the boss pretty much forever regening).
For the battle itself: Guard,. panic, scream, rinse repeat. If you get low use your bandages. You can also keep the taser if you want to get a good amount of damage in (stuns).
Also while I'm here, anyone else run into the weird red lady at the dead body? I haven't been able to recreate her appearance even after resetting.